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Otolaryngology, ENT & Sinus News Provided by the California Sinus CentersDelayed lymph node metastases after elective neck dissection in patients with oral and oropharyngeal cancer and pN0 neck - Corrected ProofJanuary 4, 2012, 12:00 pm by American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in PressAbstract: Purpose: Patients with surgically treated head and neck cancer and clinical N0 neck with high risk of occult lymph node metastasis undergo elective neck dissection (ND). Late lymph node metastasis may appear in those patients with pN0 neck. The aim of the present study was to analyze the incidence and clinical relevance of late lymph node metastasis in patients with head and neck cancer.Materials and Methods: The clinical data of 61 patients with head and neck cancer who had undergone elective ND with pN0 neck were retrospectively analyzed. Only patients without local failure, second primary, or radiochemotherapy were included in the study.Results: Late lymph node metastasis could be observed in 4 (6.5%) cases at the margin or outside the initially dissected lymph node levels. In those patients, the primary tumor was localized in the oral cavity (n = 3) or oropharynx (n = 1) and was classified in all cases as T1 or T2. Lymph node metastasis could be found in levels I (n = 2), II (n = 1), and IV (n = 1), respectively.Conclusion: Even in the case of pN0 neck after an elective ND, the appearance of late lymph node metastases must be expected. The low proportion of patients with late lymph node metastases after a selective ND in clinical and histologic N0 does not justify an extended form of neck surgery.
More from American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press Ototoxicity of Burow solution on the guinea pig cochlea - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: May 7, 2012, 12:00 pm Abstract: Purpose of the study: The aim of the present study was to evaluate the ototoxicity of Burow solution.Procedures: Compound action potentials (CAPs) of the eighth nerve were measured before and 30 Vocal characteristics in patients with thyroiditis - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: May 7, 2012, 12:00 pm Abstract: Objective: The aim of the present study was to describe the vocal characteristics of patients with thyroiditis in a clinical setting.Materials and methods: A total of 17 consecutive patients with the Bilateral enlarged vestibular aqueduct with associated bilateral Mondini dysplasia - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: April 26, 2012, 12:00 pm Abstract: Enlarged Vestibular Aqueduct (EVA) and Mondini's dysplasia ( incomplete partitioning type II) are entitites that have been fairly well described in the literature as potential causes of hearing loss in the Pattern of expression of cyclooxygenase-2 in malignant transformation of sinonasal inverted papilloma - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: April 26, 2012, 12:00 pm Abstract: Objective: Cyclooxygenases (COXs) are enzymes that catalyze the conversion of arachidonic acid to prostaglandins. Many studies have suggested that COX-2, the inducible form of COX, is important in carcinogenesis. However, little Etiology of unilateral hearing loss in a national hereditary deafness repository - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: April 26, 2012, 12:00 pm Abstract: Purpose: The aim of this study was to characterize the genetic, audiologic, and epidemiologic characteristics of unilateral hearing loss (HL) in a national hereditary deafness repository.Materials and Methods: This is a
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