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Natural History of Cervical Paragangliomas: Outcomes of Observation of 43 Patients [Original Article]

March 19, 2012, 12:00 pm by Archives of Otolaryngology Head & Neck Surgery

Objective  To evaluate the outcomes, growth rate, and symptoms of nonoperated cervical paragangliomas. Design  Retrospective review of clinical and radiologic records and images. Setting  Tertiary academic medical center. Patients  We studied all patients presenting with cervical paragangliomas between 1993 and 2010 who were observed rather than operated on. Main Outcome Measures  Growth of tumors and need for surgical removal. Results  Forty-three patients with 47 tumors were identified. Mean patient age was 56 years (age range, 17-86 years). Thirty patients were asymptomatic (70%) (22 diagnosed by imaging for other reasons and 8 for workup of a neck mass), and only 5 presented with cranial nerve abnormalities (12%). No patients presented with lymphadenopathy, rapid growth, or pain. Reasons for observation were patient preference (n = 15; 35%), advanced age of patient (n = 12; 28%), and preexisting contralateral cranial nerve deficits (n = 11; 26%). Twenty-eight of the 47 tumors were suspected carotid body tumors based on imaging (60%), and 19 were suspected vagal tumors (40%). The mean greatest dimension at presentation was 2.6 cm (range, 1-7.2 cm). During a mean follow-up of 5 years (range, 1-17 years), 19 tumors remained stable in size (42%); 17 grew (38%); and 9 regressed (20%). Of the 17 tumors that grew, the mean growth was 0.2 cm/y. Conclusions  Observation of cervical paragangliomas is an option in selected patients who do not present with worrisome symptoms. The natural history of paragangliomas in these patients is typically little to no growth over time. Regular follow-up is important to ensure minimal change and stable symptoms.

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Incidence of Pediatric Acute Mastoiditis: 1997-2006 [Original Article]
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Complications of Adenotonsillectomy in Patients Younger Than 3 Years [Original Article]
Archives of Otolaryngology Head & Neck Surgery: April 1, 2012, 12:00 pm
Objective  To evaluate the complication rate for adenotonsillectomy in children younger than 3 years, without a diagnosis of severe obstructive sleep apnea, to assess the necessity for postoperative inpatient admission. Design  Retrospective medical


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