Patient Testimonials

ENT Research at the California Sinus Centers

 

Otolaryngology, ENT & Sinus News Provided by the California Sinus Centers

Ototoxicity of Burow solution on the guinea pig cochlea - Corrected Proof

May 7, 2012, 12:00 pm by American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press

Abstract: Purpose of the study: The aim of the present study was to evaluate the ototoxicity of Burow solution.Procedures: Compound action potentials (CAPs) of the eighth nerve were measured before and 30 minutes after the application of the Burow solution in the middle ear cavity.Results: Use of the original Burow solution (pH 3.5) for 30 minutes caused a significant reduction of click sounds. A 2-fold diluted Burow solution (pH 4.4) for 30 minutes caused no reduction in CAP threshold. Burow solution, pH adjusted to 4.5, caused no changes in CAP threshold at 30 minutes. At 24 hours, Burow solution (pH 3.5) caused complete abolition of CAP.Conclusions: Burow solution is ototoxic in the guinea pig when applied in the middle ear cavity for 30 minutes or longer. In the clinical settings, it is advisable to avoid allowing the solution to contact the round window for extended times.

Read the full article


More from American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press

Predictive factors and outcomes of cochlear implantation in patients with connexin 26 mutation; a comparative study
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: August 26, 2014, 12:00 pm


FoxP3 and Indoleamine 2,3-dioxygenase Immunoreactivity in Sentinel Nodes from Melanoma Patients
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: August 22, 2014, 12:00 pm


Warfarin Induced Sublingual Hematoma: a Ludwig Angina Mimic
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: August 20, 2014, 12:00 pm


Uremuc Leontiasis Ossea
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: August 20, 2014, 12:00 pm


Paraganglioma of the Facial Canal: a Report of 2 Cases and Literature Review
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: August 20, 2014, 12:00 pm


 

NOTICE: The CSC web site "Otolaryngology ENT Industry News" has data and links presented by way of the above mentioned RSS news feeds. We offer this industry news for your convenience and education. CSC does not review the information provided in this section. CSC does not assume any endorsement or present these third-party feeds and links as CSC belief or in conjunction with CSC whatsoever. While we try to select appropriate feeds to prevent objectionable content from being displayed, the presence of any article does not indicate endorsement or recommendation by the California Sinus Centers. For more information, please see our disclaimer.