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Smoking and chronic rhinitis: effects of nasal irrigations with sulfurous-arsenical-ferruginous thermal water: A prospective, randomized, double-blind study - Corrected Proof

April 23, 2012, 12:00 pm by American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press

Abstract: Purpose: Smoking is a self-destructive behavior that is known to induce remodeling of the lower airways, leading to squamous metaplasia, but little is known about its effects on the nose and paranasal sinuses. Nasal irrigations are often mentioned as measures for treating sinonasal inflammations. The purpose of our study was to compare the effects of nasal irrigations with sulfurous-arsenical-ferruginous thermal water or isotonic sodium chloride solution in smokers with nonallergic chronic rhinosinusitis, based on clinical and olfactory evidence.Materials and methods: The present study was a prospective, randomized, double-blind study performed in a tertiary academic referral center. Seventy smokers with nonallergic chronic rhinitis were enrolled. Nasal endoscopy, rhinomanometry, nasal cytology, and odor threshold measurements were performed in subjects randomized to daily nasal irrigations with either thermal water or isotonic sodium chloride solution for 1 month.Results: Immediately after the treatment, the thermal water irrigations revealed a positive pharmacologic action, judging from a tendency toward lower nasal resistances (P = .07) and larger numbers of ciliated cells in the patients treated (P = .003). Endoscopic findings in the thermal water group were still better than in the control group a further 2 months later (P = .03).Conclusions: Our results indicate that nasal irrigations with thermal water had a good effect on endoscopic objective signs, nasal resistances, and epithelial trophism.

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More from American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press

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American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: June 6, 2013, 12:00 pm
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Incidence trends and long-term survival analysis of sinonasal rhabdomyosarcoma - Corrected Proof
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: June 5, 2013, 12:00 pm
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Taste and smell function in chronic disease: A review of clinical and biochemical evaluations of taste and smell dysfunction in over 5000 patients at The Taste and Smell Clinic in Washington, DC - Corrected Proof
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: June 3, 2013, 12:00 pm
Abstract: Purpose: To describe systematic methods developed over 40years among over 5000 patients at The Taste and Smell Clinic in Washington, DC to evaluate taste and smell dysfunction.Materials and Methods: A tripartite

Management of sinonasal teratocarcinosarcoma: A systematic review - Corrected Proof
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: June 3, 2013, 12:00 pm
Abstract: Purpose: Sinonasal teratocarcinosarcoma (SNTCS) is a rare and highly malignant neoplasm that often involves the anterior skull base. This study reviews the published literature related to SNTCS. Clinical presentation, demographics, radiographic

 

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