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Smoking and chronic rhinitis: effects of nasal irrigations with sulfurous-arsenical-ferruginous thermal water: A prospective, randomized, double-blind study - Corrected Proof

April 23, 2012, 12:00 pm by American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press

Abstract: Purpose: Smoking is a self-destructive behavior that is known to induce remodeling of the lower airways, leading to squamous metaplasia, but little is known about its effects on the nose and paranasal sinuses. Nasal irrigations are often mentioned as measures for treating sinonasal inflammations. The purpose of our study was to compare the effects of nasal irrigations with sulfurous-arsenical-ferruginous thermal water or isotonic sodium chloride solution in smokers with nonallergic chronic rhinosinusitis, based on clinical and olfactory evidence.Materials and methods: The present study was a prospective, randomized, double-blind study performed in a tertiary academic referral center. Seventy smokers with nonallergic chronic rhinitis were enrolled. Nasal endoscopy, rhinomanometry, nasal cytology, and odor threshold measurements were performed in subjects randomized to daily nasal irrigations with either thermal water or isotonic sodium chloride solution for 1 month.Results: Immediately after the treatment, the thermal water irrigations revealed a positive pharmacologic action, judging from a tendency toward lower nasal resistances (P = .07) and larger numbers of ciliated cells in the patients treated (P = .003). Endoscopic findings in the thermal water group were still better than in the control group a further 2 months later (P = .03).Conclusions: Our results indicate that nasal irrigations with thermal water had a good effect on endoscopic objective signs, nasal resistances, and epithelial trophism.

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More from American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press

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American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: April 7, 2014, 12:00 pm
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American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: March 31, 2014, 12:00 pm
Abstract: Anaplastic Thyroid Cancer (ATC) is an unusual tumour with the worst prognosis among thyroid malignancies. Treatment of the patients diagnosed with ATC is not standardized and the feasible options include surgery,

Amniotic Membrane in Reconstraction of larynx Following Chondro sarcoma Resection: a case report - Accepted Manuscript
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: March 28, 2014, 12:00 pm
Abstract: Chondrosarcomas of the larynx are rare malignancies and frequently located in cricoid cartilage. They are characterized by a low tendency to metastasis (low grade type). The treatment of choice is surgery,

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American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: March 28, 2014, 12:00 pm
Abstract: Introduction: There is an increased demand to improve facial appearance and preserve a youthful appearance for as long as possible. Minimally invasive facial procedures have boomed among young patients with less

Commentary on “How to avoid mucocele formation under pedicled nasoseptal flap” - Accepted Manuscript
American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: March 28, 2014, 12:00 pm
We read with great interest the letter by Karligkiotis et al. which characterizes techniques for avoiding mucocele formation following skull base reconstruction with pedicled nasoseptal flaps. This letter was in response

 

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