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Otolaryngology, ENT & Sinus News Provided by the California Sinus CentersThe intraparotid facial nerve schwannoma: a diagnostic and management conundrum - Corrected ProofDecember 21, 2011, 12:00 pm by American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in PressAbstract: Objectives: The aims of the study were (1) to review the management strategy and clinical outcomes of all intraparotid facial nerve (FN) schwannomas (PFNSs) treated at a single tertiary academic center from 1975 to 2010 and (2) to summarize all previously reported cases of PFNS in the international literature.Study design: A retrospective cohort study and literature review.Methods: Fifteen patients were diagnosed and treated at the authors' institution from 1975 to 2010. In addition, 124 published cases were systematically reviewed.Results: The most common presentation of PFNS was a painless parotid mass with normal FN function. Eccentric, loosely attached intraparotid tumors underwent gross total resection with nerve preservation granting satisfactory postoperative FN function, whereas “inseparable” intraparotid tumors were observed in 8 cases with stable long-term size. Lesions that extended into the fallopian canal underwent complete resection with FN sacrifice and nerve grafting in 10 cases, whereas 1 patient received subtotal resection of the intraparotid portion with stereotactic radiotherapy targeting the intratemporal component.Conclusions: Intraparotid FN schwannomas present similar to other primary salivary gland neoplasms, making an early diagnosis challenging. Intraoperative recognition of gross tumor characteristics and early histologic diagnosis with strategic biopsy are critical. Information including tumor location and extent, preoperative FN function, and the gross relationship between the tumor and the FN may guide the surgeon toward an optimal treatment plan emphasizing long-term neurologic preservation.
More from American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press Ototoxicity of Burow solution on the guinea pig cochlea - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: May 7, 2012, 12:00 pm Abstract: Purpose of the study: The aim of the present study was to evaluate the ototoxicity of Burow solution.Procedures: Compound action potentials (CAPs) of the eighth nerve were measured before and 30 Vocal characteristics in patients with thyroiditis - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: May 7, 2012, 12:00 pm Abstract: Objective: The aim of the present study was to describe the vocal characteristics of patients with thyroiditis in a clinical setting.Materials and methods: A total of 17 consecutive patients with the Bilateral enlarged vestibular aqueduct with associated bilateral Mondini dysplasia - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: April 26, 2012, 12:00 pm Abstract: Enlarged Vestibular Aqueduct (EVA) and Mondini's dysplasia ( incomplete partitioning type II) are entitites that have been fairly well described in the literature as potential causes of hearing loss in the Pattern of expression of cyclooxygenase-2 in malignant transformation of sinonasal inverted papilloma - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: April 26, 2012, 12:00 pm Abstract: Objective: Cyclooxygenases (COXs) are enzymes that catalyze the conversion of arachidonic acid to prostaglandins. Many studies have suggested that COX-2, the inducible form of COX, is important in carcinogenesis. However, little Etiology of unilateral hearing loss in a national hereditary deafness repository - Corrected Proof American Journal of Otolaryngology - Head and Neck Medicine and Surgery - Articles in Press: April 26, 2012, 12:00 pm Abstract: Purpose: The aim of this study was to characterize the genetic, audiologic, and epidemiologic characteristics of unilateral hearing loss (HL) in a national hereditary deafness repository.Materials and Methods: This is a
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