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Otolaryngology, ENT & Sinus News Provided by the California Sinus CentersThyroid Cancer Outcomes in Filipino Patients [Original Article]February 1, 2010, 12:00 pm by Archives of Otolaryngology Head & Neck SurgeryObjective To compare the outcomes of patients having thyroid cancer among Filipinos vs non-Filipinos. Design Retrospective medical record review. Setting High-volume tertiary referral center in Toronto, Ontario, Canada. Patients A total of 499 patients with thyroid cancer (36 Filipino and 463 non-Filipino) treated at Mount Sinai Hospital from January 1, 1984, to August 31, 2003, with a minimum 5-year follow-up period and a minimum 1.0-cm tumor size. Patients were identified from a thyroid cancer database. Data on patient, tumor, and treatment factors were collected along with outcomes. Main Outcome Measures The presence of thyroid cancer recurrence, the rate of death from disease, and the time to recurrence. Results The 2 groups were similar for sex, age, history of head and neck radiation exposure, family history of thyroid cancer, follow-up time, tumor size, tumor pathologic findings, presence of tumor multifocality, stage of primary disease, type of thyroid surgery, use of postoperative radioactive iodine therapy, and use of external beam radiation therapy. Filipino patients experienced a thyroid cancer recurrence rate of 25% compared with 9.5% for non-Filipino patients (odds ratio, 3.20; 95% confidence interval, 1.23-7.49; P = .004). On multivariate analysis, the increased risk of thyroid cancer recurrence persisted for Filipino patients (odds ratio, 6.99; 95% confidence interval, 2.31-21.07; P < .001). No significant differences were noted between Filipino patients and non-Filipino patients regarding the rate of death from disease (5.6% vs 1.9%) and the time to recurrence (52.6 vs 53.1 months). Conclusions Filipino patients have a significantly higher risk of thyroid cancer recurrence compared with non-Filipino patients. However, no significant difference was noted in the time to recurrence or the rate of death from disease. These findings justify a more aggressive initial management and follow-up regimen for Filipino patients with thyroid cancer.
More from Archives of Otolaryngology Head & Neck Surgery Long-term Results of Radiofrequency Turbinoplasty for Allergic Rhinitis Refractory to Medical Therapy [Original Article] Archives of Otolaryngology Head & Neck Surgery: July 19, 2010, 12:00 pm Objective To study the long-term outcomes of radiofrequency (RF) turbinate surgery for the treatment of allergic rhinitis refractory to medical therapy.Design A retrospective review of a prospective data set.Setting Tertiary referral center.Patients Sea view at Palma de Mallorca [About the Cover] Archives of Otolaryngology Head & Neck Surgery: July 1, 2010, 12:00 pm About This Journal [About This Journal] Archives of Otolaryngology Head & Neck Surgery: July 1, 2010, 12:00 pm Lack of Financial Barriers to Pediatric Cochlear Implantation: Impact of Socioeconomic Status on Access and Outcomes [Original Article] Archives of Otolaryngology Head & Neck Surgery: July 1, 2010, 12:00 pm Objectives (1) To analyze if socioeconomic status influences access to cochlear implantation in an environment with adequate Medicaid reimbursement. (2) To determine the impact of socioeconomic status on outcomes after unilateral cochlear Propranolol in the Management of Airway Infantile Hemangiomas [Original Article] Archives of Otolaryngology Head & Neck Surgery: July 1, 2010, 12:00 pm Objective To report our experience with propranolol in managing airway infantile hemangiomas. Design Case series of 3 consecutive patients who had extensive, symptomatic airway infantile hemangiomas treated with propranolol. Setting Tertiary academic medical center. Patients
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